Clinicoradiologic Correlations of Cerebral Microbleeds in Advanced Age

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Clinicoradiologic Correlations of Cerebral Microbleeds in Advanced Age.

BACKGROUND AND PURPOSE The presence of cerebral microbleeds has been associated with dementia and cognitive decline, although studies report conflicting results. Our aim was to determine the potential role of the presence and location of cerebral microbleeds in early stages of cognitive decline. MATERIALS AND METHODS Baseline 3T MR imaging examinations including SWI sequences of 328 cognitive...

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Cerebral microbleeds in a neonatal rat model

BACKGROUND In adult humans, cerebral microbleeds play important roles in neurodegenerative diseases but in neonates, the consequences of cerebral microbleeds are unknown. In rats, a single pro-angiogenic stimulus in utero predisposes to cerebral microbleeds after birth at term, a time when late oligodendrocyte progenitors (pre-oligodendrocytes) dominate in the rat brain. We hypothesized that tw...

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Cerebral microbleeds: histopathological correlation of neuroimaging.

BACKGROUND In recent years, there has been a growing interest in cerebral microbleeds (CMBs) and their role in cerebrovascular disease. A few studies have investigated the histopathological correlation between CMBs and neuroimaging findings. We conducted a systematic review in an attempt to characterize the pathological and radiological correlation. METHODS A systematic literature search was ...

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Cerebral microbleeds and depression in lacunar stroke.

BACKGROUND AND PURPOSE Cerebral microbleeds (CMB) are common in stroke survivors and the community-dwelling elderly. The clinical significance of CMB in the development of depression after a stroke is unknown. This study examined the association between poststroke depression (PSD) and CMB. METHODS A cohort of 235 patients with acute lacunar stroke admitted to the stroke unit of a university-a...

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Prevalence and Risk Factors of Cerebral Microbleeds

Background and Purpose—We previously reported on the high prevalence of cerebral microbleeds (CMBs) in community-dwelling people aged 60 years and older. Moreover, we found that their spatial distribution likely reflects differences in underlying etiology. We have since almost quadrupled the number of participants in our study and expanded it to include persons of 45 years and older. We examine...

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ژورنال

عنوان ژورنال: American Journal of Neuroradiology

سال: 2016

ISSN: 0195-6108,1936-959X

DOI: 10.3174/ajnr.a4956